Etiology

• CVD - Atherosclerosis

Pathogenesis

• Plaque build-up in the lumen of coronary arteries (Ca, Cholesterol, inflammatory cells, w/ fibrous cap )

  • Ischemia Cascade

    

  • 70% blockage = S/S onset

  • 90% = S/S at rest

Classification

• Chronic
• Vaso-spastic (Prinzmetal)

Presentation

Signs and Symptoms

• CP - Chest Pain → Typical Angina Pectoris (can be typical or atypical)

Investigation

Functional Test (stress tests) → Screening

Stress:

• Exercise Stress Test (preferred)
• Dobutamine (for people who cannot exercise: Frailty, RA - Rheumatoid Arthritis

Tests:

Structural Tests → Diagnosis

• CTA (CT Arterial Phase)
• Coronary Angiogram / Cath Lab