Pathogenesis

Pathway involved:

#Depressant, #Gaba, #Glutamate

Screening

CAGE questionnaire

Investigations

• GGT (< 50)
• Transaminitis: AST (< 40) > ALT→ Think about Alcohol (RF)
• MCV (80-100) → Macrocytic Anemia (> 100)
• Peripheral Blood Film → round macrocyte

Treatment

Non-pharma

1. Education, Motivational Interview
2. RAAMP
3. MAARS Maintenance: AA, smart recovery, rehabilitation program

Pharma