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💡 *In anyone with a uterus, Estrogen treatment must be combined with Progesterone-related drugs to avoid Uterine hyperplasia .
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Effects
- Shredding of uterine lining
- Increases sex-hormone binding androgen → reduce circulating testosterone → anti-androgen effect
- For Pre-term Labour (PTL) : Increase cervical length
- Weight gain → Progesterone stimulates deposition of body fat but had catabolic effects on protein metabolism → Link
Examples
Admin
- Cyclic: Q10 days, can be PO, Vaginal, or IV/IM/Sc
- Continuous: PO, IV/IM/Sc, LNG-IUD
- POP: As a “Mini pill” for oral contraception → need to take at the same time every day
Additional Benefits:
