Type of Metastasis

• Lymphatic
• Hematological
• Transcoelomic:
  • A route of tumour metastasis across a body cavity, such as the pleural, pericardial, or peritoneal cavity

Process

Adenocarcinoma :

• 1st step : loss contact inhibition (cells crowd the duct) -> carcinoma in situ
• 2ed step: break basement membrane
• 3rd step: spread through various levels of lymph node
  • e.g. Breast: level 1 -> 2 -> 3 or hematological