a.k.a. Marijuana
Drug
Type
MOA
Psychotic Effects
THC
Hallucinogen,
Activates CB1 receptors, disrupting normal neurotransmitter release (dopamine, glutamate, GABA, serotonin)
paranoia, delusions, hallucinations, disorganized thinking
CBD
Depressant
With enough THC, some people may get
Psychosis
, some will not
lead to earlier onset of schizophrenia, increase schizophrenia symptoms
there are some people who have schizophrenia and use cannabis, they wouldn’t have schizo if had not been cannabis use
Intox
Sedating
First 24-72 hr of use → high risk of psychosis → Early-onset schizophrenia
Withdrawal
Agitating
Severe anxiety
