Do not cover anaerobe

1st gen: Cephalexin (1 gen PO) po, Cefazolin (1 gen IV) IV

2nd gen: Cefuroxime po or IV, Cefprozil po, Cefoxitin IV

• Gram + mostly, MSSA

3rd gen: Cefixime (3 gen PO) po, CTX - Ceftriaxone (3 gen IV) IV, Cefotaxime (3 gen IV) IV, Ceftazidime (3 gen, IV/IM)

• GN > GP (GP need higher dose)

4th gen: Cefepime (4 gen IV)

• GP and GN including Pseudomonas
• Cefepime, good for Pseudo Monas
• Dime and Pime = Pseudo Monas :)

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