Encompases:

• Chemotherapy
• Immunosuppression drugs

Definition:

Drugs that kill or severely damage cells, especially rapidly dividing cells (including cancerous cells and certain immune cells).

Mechanism:

• Disrupting DNA/RNA synthesis directly or indirectly (alkylation, DNA intercalation).
• Inducing apoptosis or cell death pathways.

Clinical Uses:

• Cancer chemotherapy
• Severe autoimmune disorders (often lower-dose than oncology regimens)
• Immunosuppression in specific aggressive autoimmune or inflammatory conditions (e.g., lupus nephritis, vasculitis)