<aside>
| Category | Disease | Abx | Abx Duration |
|---|---|---|---|
| ‣ | Ealry Onset (<72hr) (GBS, E. coli, other GN, Listeria) | Ampicillin + Gentamicin | |
| *7–14 days | |||
| ***Negative Culture: Stop after 48h | |||
| Late Onset (CoNS, S. aureus, GN, Candida) | Vancomycin + Gentamicin | 7–14 days | |
| Lung | Neonatal pneumonia (GBS, E. coli, other GNs, Listeria | Ampicillin + Gentamicin | 7–14 days |
| ‣ | Gram-positive meningitis (GBS), Listeria monocytogenes | Ampicillin + Cefotaxime | 21 days |
| Gram-negative meningitis (E. coli, Klebsiella) | — | ≥21 days | |
| ‣ | Medical NEC (E. coli, Staph, Kleb, Proteus, C.diff) | Pip/Tazo or Ampicillin + Gentamicin + Metronidazole | 5–7 days |
| Surgical/severe NEC | — | 10–14 days | |
| UTI | UTI (E. coli) | Ampicillin + Gentamicin | 7–14 days |
| ‣ | HSV (SEM) | IV Acyclovir | 14 days |
| HSV (CNS/disseminated) | — | 21 days |
| Bacteria | Causes |
|---|---|
| ‣ | NEC, UTI, Meningitis, Sepsis, Pneumonia |
| ‣ | Meningitis, Sepsis, Pneumonia |