• 20% of Cardio output goes to Kidney

Glomerulus Filtration Rate (> 90 ml/min, 125 L/day)

Def. Sum of all filtration that occurs in all of the nephrons in the body

• Lab measurement: Inulin, Lothalamte (nuclear medicine)
• Clinical:
  • Measured by creatine clearance: 24 Urine Sample (Urine Creatine) vs sCr (60-100 umol/L)
  • Estimated (eGFR (≥ 60mL/min) ) by sCr (60-100 umol/L)

Regulation

Measurement