• Composition: Formed from Tamm-Horsfall protein, which is a glycoprotein secreted by renal tubular cells.
• Appearance: These casts are typically clear and colorless, and they can be seen in various conditions, including dehydration and vigorous exercise.
• Clinical Significance: While hyaline casts are non-specific, their presence in MM - Multiple Myeloma patients can indicate tubular injury or stress.