Mild cognitive impairment

Diagnosis

• Subjective cognitive changes: Patient self-report (or collateral)
• Objective cognitive changes: Positive MOCA (≥26/30) or MMSE (≥24/30)
  • Not necessary to make the diagnosis
• Function not affected (ADL and IADL NOT impaired)
• R/O reversible causes
  • Delirium
    • you CAN diagnose MCI when the patient have delirium:
      • Based on patient self-report (or collateral)
      • Don’t need to administrate MOCA and MMSE (a lot of other factors, such as medication, would affect its result)
  • Depression Symptom
  • Severe Hypothyroidism ↓
  • Alcohol (RF) use (> 3 units per day)

Amnestic MCI

• Conversion rate to AD - Alzheimer’s Disease of 10-12% per year, 80% after 6 years

If function is impaired (directly as a result of cognition) → Dementia