(Total number of chromosome including sex chromosome, sex chromosome)
Genetic male = 46, XY
Genetic female = 46, XX
Down syndrome (male) = 47, XY, +21
Klinefelter Syndrome = 47, XXY
Turner’s Syndrome = 45, X
| Component | Outcome |
|---|---|
| SRY/TDF | Testis (direct), internal and external genitalia (downstream) |
| ‣ | Male internal genitalia (Woffian system = vas deferens, seminal vesicle) |
| ‣ | Male external genitalia (penis, glan penis, scrotum) |
| AMH/MIF + SOX9 | Regression of female internal genitalia (Mullerian system = uterine tube, uterus), SOX9 |
