Effect: slow down the progression of lung fibrosis

Conditions:

• Only covered for IPF - Idiopathic Pulmonary Fibrosis

CI:

• Smoking
• Kidney failure
• Liver failure

MOA: regulate cytokine cascade → Reduces fibroblast proliferation & collagen synthesis

Admin: 3 capsules of 267mg po TID

Pro: Proven to have mortality benefit

Con: expensive $40,000

Side effects:

• GI
• Rash / Photosensitivity