‣
blocks AA, prevent the access of the enzyme
Trough > 50 - kidney toxicity
ONLY GP
Targeted
MRSA
Enterococcus Species
UTI
Resistent
Streptococcus pneumnonia
Monitor & Target
Abx trough/peak level
before 4th dose
(10-)15 mg
Most infection
(15-)20 mg
Very deep infection