Systemic Autoimmune Rheumatic Disease

Can also be referred to as ‘Connective Tissue Disease’ or ‘Collagen Vascular Disease’

• Not to be confused with True CTD → have genetic causes
• Autoimmune Disease characterized by inflammation in tissues (NOT auto-inflammatory)
  • Characteristic patterns of organ involvement
  • Characteristic antibody profiles

Conditions

Undifferneciated Collagen Vascular Disease

RA - Rheumatoid Arthritis

SLE - Lupus

Inflammatory Myositis

Scleroderma

Sjogren’s Disease

Overlap Syndrome

Mixed Connective Tissue Disease

Investigation Principle