Def.

• Perimenopause: 5-7 yrs preceding menopause
• Average ago in NA: 52
• Early menopause: age 40-45
• Premature menopause: age < 40

Presentation

• VMS - Vasomotor symtom
• GSM - Genitourinary Syndrome of Menopause
• Insomnia/Sleep disturbances
• Cognitive impairment and Mood Disturbances

Signs and Symptoms

80% experience either VMS or GSM

Chronic Complications

• Brain
  • VMS - Vasomotor symtom → 3 yr peri-menopause
  • Depression Symptom (mood changes)
  • Memory problems
• Bone
  • OP - Osteoporosis
  • Fractures
• Heart
  • Higher risk of CVD - Atherosclerosis
    • CAD
    • Carotid Disease