Urinary Frequency, Urgency, May have Urge incontinence

Pathogenesis

• Overactive detrusor muscle activation (under PNS control)

  

Etiology

• Idiopathic
• Neurogenic : Neurogenic bladder
  • MS - Multiple Sclerosis
  • Parkinsonism
  • After !Stroke (CVA)
• Non-neurogenic
  • bladder stone
  • UTI
  • BPH

Treatment

1. Life style modification (reduce coffee and fluid intake, timed voiding)
2. Pelvic Floor Physio
3. Medication “A, B”
   • Non-selective/M3 Anti-ACh
   • β3 Agonist (Beta-3)
     • Mirabegron (Myrbetriq®)
4. Intravesicular Botox Injection
5. Advanced therapy
   • Neurostimulation
   • Urinary Diversion