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PAP Smear → Cytology

Sampling

New: Cervical Screening Test

Cervical Sample → HPV DNA Test (+/- automatic cytology if possible)

Q5 yr

If positive → Pap smear

2025 Guideline

https://www.cancercareontario.ca/sites/ccocancercare/files/assets/OCSP-Guide-To-Cervical-Screening-EN.pdf

*Cervical Screening Test Does Not test for low risk (non-oncogenic) variant → HPV 6, 8 (genital warts).

*Cervical Screening Test Does Not test for low risk (non-oncogenic) variant → HPV 6, 8 (genital warts).

Test Result Interpretation

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Summary

Result Next Step
HPV - Continue Q5 yo
HPV 16, 18/45, or high-grade cytology with other HPV variant Colpscopy (Diagnostic test for )
low-grade cytology with other HPV variant Repeat Cervical Screening Test in 2 yo → Colpscopy if still HPV+
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