A PTH analogue

Effect:

• Limited non-vertebral fracture benefit

Conditions:

• OP - Osteoporosis with bad Vertebral Fracture Hx

Side effects:

• !Hypercalcemia - ↑Ca (> 2.5)
• Hypotension ↓(<90/60) (1st few doses)
• N/V - Nausea/vomitting
• Muscle Cramp
• Headache
• Gout

MOA:

• At low dose, has paradoxical bone-reforming effect