| Feature | ‣ | ‣ | ‣ |
|---|---|---|---|
| Granulomas | Yes | Yes (+ eosinophils) | |
| ANCA | PR3-ANCA (c-ANCA) | MPO-ANCA (p-ANCA) | MPO-ANCA (p-ANCA, 40%) |
| Lungs | Nodules, cavitation, hemorrhage | Hemorrhage | Asthma, transient infiltrates |
| Kidneys | RP ‣ | RP ‣ | GN (less common/severe) |
| Unique clue | ENT involvement: Saddle-nose, cavitary lung nodules | +/- ‣ | Asthma + eosinophilia |