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Etiology

Spontaneous Pre-term Birth

Refer to Pre-term Labour (PTL)

Normal Labour Pre-term Labour Causes Etiology Tests Tm Summary
Membrane Activation ‣ 90% infection → From GU Infection (BV, C/G, rUTI, ‣ ) Fetal fibronectin (fFN) Abx, get ready for birth
Cervical Dilation Cervical Insufficiency 1) shorter <2.5 cm, 1.5 cm → 30-40% chance of PTL
  1. early effacement | Cervical Length (3-4 cm) | ‣ - short cervix

‣ - mechanical weakness | | Uterine Contraction | ↑ uterine stretch | GDM - Gestational Diabetes , ‣, Intramural ‣, Uterine Anomalies (bicornuate, unicornuate) | ‣ | ‣ |

Iatrogenic Pre-term Birth

!Pre-eclampsia

GDM - Gestational Diabetes

IUGR/FGR

Epidemiology

Survival Rates among infants admitted to the NICU

Survival Rates among infants admitted to the NICU

Neurodevelopmental impairment at 21 months: 220-286 weeks, Canada (2009-2011)

Neurodevelopmental impairment at 21 months: 220-286 weeks, Canada (2009-2011)

Investigations

Management

Goals: improve neonatal outcomes

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