The alpha-1 protein is designed to protect tissues in the body from being attacked by its own enzymes (trypsin, protease).

The only genetic cause of COPD

Increased risk of:

• COPD → almost always occur in adults
• Liver and skin problems → may occur in adults and children
  • Liver diseases , and COPD
  • skin problems (Panniculitis ),
  • inflammation of the blood vessels (Vasculitis ).

Alpha-1-antitrypsin deficiency - About the Disease - Genetic and Rare Diseases Information Center

Treatment

• IV AAT
• ICS (’onide’, ‘asone’), Bronchodilators
• Other treatments for COPD