Approach

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DDx + Key Investigation

Detailed Flow Chart

Detailed Flow Chart

Condition Onset # of Joint Involved Red Flags/Key symptom Next Step
🦠!Septic Arthritis Acute 1-3 Painful swollen red joint, Hx of ⌛!Open Fracture 🧪SFA - Synovial Fluid
💥Crystalline Arthritis - 💥Gout Acute 1-3 EXTREMELY Painful swollen red joint- Hx of 🫘CKD , 🍻Alcohol, ⏳Menopause 🧪SFA - Synovial Fluid
Trauma Acute 1-3 Hx of Trauma 🧪SFA - Synovial Fluid, 2 Plane XR (Bone and Joint)

Diagnosis Based on Synovial Fluid

Common Marker Normal Non-inflammatory Arthritis () ( in mono) !Septic Arthritis !hemoarthrosis
Appearance yellow transparent yellow transparent exudative Opaque, exudative Bloody Translucent
Viscosity + + - variable variable
WBC count <200 200-2,000 >2,000 >80,000 (some says 50,000) 2,000 - 80,000
PMN <25% <25% > 50% >75% 50-75%
Next Step - Special Test Microscopy (Crystals) GS, C & S Cytology