Red flags:

• Progressive deep pain, night pain
• Palpable mass
• Soft tissue swelling
• Lymphadenopathy
• Pathological Fracture → stabilize, irradiate, treat systemic cancer, involve palliative care.

Common primary → blt-pk (BLT with a Kosher Pickle)

• B: Breast cancer
• L: Lung Cancer
• P: Prostate cancer
• R: Renal Cancer - RCC
• T: Thyroid Cancer

“Bone lysis (is) really painful too”

Complication → Spine metastasis, !Hypercalcemia - ↑Ca (> 2.5)