Hyperosmolar Hyperglycemic State
| !DKA - Diabetic KetoAcidosis | !HONK/HHS | |
|---|---|---|
| Cause | Insulin Defeciency | Insulin Resistence |
| Acid-base | ‣ | NA |
| ‣ | ↑↑↑ | NA |
| Serum Osmolality (275-295) | NA or ↑ | ↑↑↑ |
| ‣ | ↓ | ↓↓↓ |
| ‣ - [K] | ‣ → H+ shift in and K+ shift out | No H+, but K+ shift out due to low insulin |
| Total Body K | ↓↓↓ (Osmotic diuresis) | ↓↓↓ (Osmotic diuresis) |
| Mortality | 0.65-3% | 12-17% |