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Sources and Distribution

Role

• RMP → Muscle, Heart, Nerves
• Decreases in K+ = peripheral vasoconstriction = increased PVR = increased BP

Regulation

• Aldosterone
• Insulin
• Serum Catecholamine

Med Affecting K

Increase: RAA (ACEi(-pril), ARB (-sartan), MRA)

Decrease: Diuretics