Dysfunction of optic nerve

Presentation (5)

DDx

Etiology Specific Diseases Key risk factors Key presentation
Vascular (eye) : and AAION/GCA: older, female
NAION: vascular risk factor Sudden-onset monocular altitudinal VFD
Inflammatory Young, female, think Pain with eyemovement, Monocular VFD
Neoplastic (Compressive)
of ICA
Optic Nerve Sheath Meningioma Slow-progressing, painless, monocular VFD
Nutritional deficiency
Hx Bilateral, symmetric
→Papilloedema
Space-occupying lesion in brain , woman, child-bearing age (IIH) Normal everything else
Bilateral Optic disc edema
, Pulsatile
Hereditary Dominant optic atrophy (AD)
Hereditary Optic Neuropathy (M) FHx AD or mitochondrial inheritance pattern

AION