• Associated with

  • Acne
  • Hirsutism

• Rapid onset Virilization : indication of androgen-secreting neoplasm of

  • Adrenal → Adrenal carcinoma
  • Ovary → Ovarian cancer

Presentation

Development of male secondary sexual characteristics

• Deeper voice
• Increased libido
• Androgenic Alopecia (Hair Loss)
• Clitoromegaly
• Infertility (maybe reversible)
• Oligo-amenorrhea
• Skin changes
• Muscle Fat distribution
• Loss of breast tissues
• Malodorous perspiration (smelly sweat)

Investigation

Investigation