Wilson disease is a genetic disorder that prevents the body from removing extra copper, causing copper to build up in the liver, brain, eyes, and other organs.

Manifestation:

• Hepatic:
  • Hepatitis, Genetic Liver Disease
  • Cirrhosis (Most common manifestation)
• Neurological:
  • Chorea , Tremor, Dystonia, Dysarthria, Ataxia,
  • Cognitive impairement
• Eye
  • Kayser-Fleischer ring
  • Sunflower cataract
• Psychiatric
  • Depression Symptom, Psychosis
  • Mania/hyponia (7/4 dys)
• MSK
  • OP - Osteoporosis
  • Polyarthritis
• Heart
• Kidney
• Hematologic
  • !Hemolysis

Additional Investigation

Brain MRI