Hemostasis, Coagulation Casecade

• Liver Synthesis Failure
  • Coagulopathy
    • Prolonged PT/INR (<1)
  • Primary Hemostasis Problems
    • VWD - Von Willebrand disease
  • Thrombosis ALI (4)
    • Anti-clotting factors
• Portal Hypertension
  • Hypersplenism → Thrombocytopenia ↓ (sequestering)
  • !Variceal UGIB