Contraindication for

• OCP

Numbers

• 20 pack-year: tipping point for lung cancer

MOA

Nicotine in Tobacco/Cigarette. Also harmful chemicals.

Psych

• Tobacco use disorder
• Smoking cessation Therapy

Long term consequences

Lung

• COPD
  • Chronic Bronchitis (’blue blower’)
  • Emphysema (’pink puffer’)
• Pneumonia
• !Acute Asthma exacerbation
• Malignancy
  • Lung Cancer
  • Bladder Cancer - TCC
  • OP Cancer Laryngeal Cancer
  • Oral Cavity Cancer
  • Also GI tract (mouth, pharynx, larynx, esophageal, stomach), pancreatic, cervical, kidney, and AML

Vascular

• CVD - Atherosclerosis (Vascular Risk Factors)
  • !MI
  • !Stroke (CVA)
  • PAD - Peripheral Arterial Disease
  • Aneurysm
    • !Cerebral Aneurysm
    • AAA - Abdominal Aortic Aneurysm
• Erectile Dysfunction

Psychiatric